Regaine for Men Extra Strength Scalp Foam 5 Percent w/w Cutaneous Foam Minoxidil , 3 Month's Supply Easy to Ese Foam, 73 ml (Pack of 3)

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Pressurized container: May burst if heated. Protect from sunlight and do not expose to temperatures above 50°C. Do not pierce or burn, even after use. Do not spray on a naked flame or any incandescent material. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not use near or place container on polished or painted surfaces. Regaine has been shown to encourage hair regrowth in as little as eight weeks, however this could be up to 16 weeks for some people. You also must bear in mind that the first six weeks of using Regaine may see a temporary increase in hair loss. What happens if I miss a dose of Minoxidil? Thanks for the comment, Mori. Yes, I’ve heard similar sentiments from others who’ve used both the foam and the liquid – that the liquid may work a bit better but that it yields more undesirable side effects. Of course, plenty of people use the liquid without issue as well. There is some evidence from in vitro studies that minoxidil reversibly binds to human plasma proteins. However, since only 1 – 2% of topically applied minoxidil is absorbed, the extent of plasma protein binding occurring in vivo after topical application would be clinically insignificant. The volume of distribution of minoxidil doses between 1.37 mg and 27.4 mg at steady state after 12-hour intravenous administration ranges from 76.0 to 82.8, respectively.

In a randomised, controlled evaluator-blind multicentre study, 5 % minoxidil topical foam (MTF) applied once a day (OD) was compared to 2% minoxidil topical solution (MTS) applied twice daily (BID), each for 52 weeks. Accidental ingestion may cause serious cardiac adverse events. Therefore this product has to be kept out of the reach of children. If hair regrowth occurs, once daily applications of this product are necessary for continued hair growth.Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Hair colouring, hair permanents or hair relaxers may be used during minoxidil treatment as long as the scalp is washed just before applying the hair colouring, permanent or relaxer. Please bear in mind, Minoxidil should not be used 24 hours before and after the hair treatment procedure. If hair growth is going to occur with the use of minoxidil, it usually occurs after the medicine has been used for several months and lasts only as long as the medicine continues to be used. Hair loss will begin again within a few months after minoxidil treatment is stopped.

Do not use any other skin products on the same skin area on which you use minoxidil. Hair coloring, hair permanents, and hair relaxers may be used during minoxidil therapy as long as the scalp is washed just before applying the hair coloring, permanent, or relaxer. Minoxidil should not be used 24 hours before and after the hair treatment procedure. Be sure to not double your doses of minoxidil to make up for any missed doses. The primary efficacy criterion was non-vellus hair count in a 1.0cm 2 reference area of affected scalp. The mean changes observed in this parameter in these studies were significantly in favour of active treatment. A significant dose effect was also demonstrated. The results are summarized in the following table: It may take once-daily applications for 12 to 24 weeks before evidence of hair growth can be expected. Users should discontinue treatment if there is no improvement seen after 24 weeks. Finasteride– finasteride is sort of the male equivalent to “the pill.” Like the female version of “the pill”— i.e. birth control — finasteride comes with an array of unpleasant, potential side effects, primarily of the sexual variety. The drug has an excellent safety profile overall and has been FDA-approved to treat hair loss for over 25 years.

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Topical drugs, such as corticosteroids, tretinoin, dithranol or petrolatum, which alter the stratum corneum barrier, could result in increased absorption of minoxidil if applied concurrently. Although it has not been demonstrated clinically, there exists the theoretical possibility of absorbed minoxidil potentiating orthostatic hypotension caused by peripheral vasodilators. This medicine usually comes with patient instructions. It is important that you read the instructions carefully. This product should not be used concomitantly with other medications applied topically on the scalp (see section 4.3). The systemic absorption of minoxidil from twice daily application of 5% minoxidil foam was about half of that observed with 5% minoxidil solution. The mean steady state AUC (0-12 hr) and Cmax for 5% minoxidil foam, 8.81 ng·hr/mL and 1.11 ng/mL, respectively, were both approximately 50 % of AUC (0-12 hr) and Cmax of the 5% solution, 18.71 ng·hr/mL and 2.13 ng/mL, respectively. Because of the concentration of minoxidil in Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam, accidental ingestion has the potential of producing systemic effects related to the pharmacological action of the drug (2 g of Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam contains 100 mg minoxidil; the maximum recommended adult dose for oral minoxidil administration in the treatment of hypertension). Signs and symptoms of minoxidil overdosage would primarily be cardiovascular effects associated with sodium and water retention. Tachycardia, hypotension, dizziness and lethargy can also occur.

Clinical Trials have not investigated the efficacy of Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam beyond 16 weeks. Assessment was undertaken by patients using a 100mm visual analogue scale and assessing scalp coverage where point 0 represented much less scalp coverage, 50mm no difference and 100mm much more scalp coverage. In addition, an assessment was undertaken by 2 blinded reviewers who compared photographs taken at baseline and after 48 weeks. Differences were assessed using a 7 point categorical scale viz:Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hypersensitivity reactions (including face oedema, generalised erythema, pruritus generalised, swelling face, and throat tightness) Adverse drug reactions (ADRs) identified during clinical trials and post-marketing experience with minoxidil are included in the table below by System Organ Class (SOC). Individual responses to Regaine for Women ONCE A DAY are variable and unpredictable. The efficacy of 5 % minoxidil topical foam for the treatment of androgenic alopecia in women has been assessed in two phase 3 clinical trials, each studying women with FPHL with scalp hair density on the top of the scalp D3 to D6 on the Savin Density Scale.

Male pattern baldness is the common type of hair loss that develops in many men at some stage. The condition is sometimes called androgenetic alopecia. It is caused by a combination of hereditary (genetic) and hormonal factors.

Does minoxidil work?

It may take twice daily applications for 2 months or more before evidence of hair growth can be expected. There are two minoxidil preparations available which are suitable for men to use - a scalp solution and a scalp foam. The scalp solution is suitable for men aged 18-65 years, whereas the foam is suitable for men 18-49 years old. Minoxidil preparations are not available on the NHS, but you can buy them, without a prescription, in pharmacies and other retail outlets. Clinical Trials have not investigated the efficacy of this product beyond 24 weeks. Further secondary results and safety were assessed up to 52 weeks (see section 5.1). There are no adequate and well-controlled studies in pregnant women. Studies in animals have shown a risk to the foetus at exposure levels that are very high compared to those intended for human exposure. There is potentially a risk of foetal harm in humans (see section 5.3).