Glucosamine and Chondroitin Complex – 180 High Strength Capsules – Contributes to The Maintenance of Normal Immune System – with Vitamin C, Turmeric, Ginger and Rosehip – Made in The UK by Nutravita

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These arthritis supplements may also have a blood-thinning effect, so people taking these supplements in addition to an anticoagulant may have to have their blood tested more often. People who are allergic to shellfish also should consult their doctors before using glucosamine and chondroitin. Glucosamine is extracted from a substance in shellfish.

MSM, or methylsulfonylmethane, is a supplement that is used to try to help a wide range of conditions, including arthritis, allergies, and even snoring. Alshammari E, Alshammari A. Glucosamine effects on lipids and blood pressure. Int J Res Pharm Sci. 2020;11(1):431-6. doi:10.26452/ijrps.v11i1.1838 If you are thinking about taking a glucosamine supplement, it’s essential to be aware of its side effects. On the whole, it’s believed to be safe for most people and side effects tend to be rare. 13 If you do notice any unwanted side effects, stop taking glucosamine and talk to your doctor if you’re concerned. With upward of 3.6% of the global population living with this debilitating condition, many people use or have tried using combined glucosamine and chondroitin supplements to alleviate osteoarthritis pain ( 2). SummaryN-acetyl glucosamine (NAG). Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Oct. 24, 2020. The most comprehensive long-term study — the Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)— compared thecombination ofglucosamine hydrochloride and chondroitin, both supplements individually, celecoxib ( Celebrex) andaplacebo(inactive pill)innearly 1,600peoplewith knee osteoarthritis. If you have decided that glucosamine supplements are right for you, it’s essential to take the correct dosage. Always read the label on your chosen product and follow the instructions carefully. Did this study or subsequent research spell the end of people taking glucosamine, chondroitin, or both? Not at all! While the evidence of benefit is certainly not compelling, some studies have found that these supplements provide modest benefit, and people who feel it is helping them may not care so much about individual studies anyway. Even if a treatment is not effective on average, there may be folks who, for whatever reason, get real relief from it. Finally, people are taking glucosamine and/or chondroitin for a number of reasons and conditions other than osteoarthritis of the hip or knee, so these studies may not apply to them. And what about the downsides?

Many physicians may still recommend a trial of glucosamine at this point, and if there is not apparent improvement by three months, it would be reasonable to stop glucosamine. Research is ongoing. Vasiliadis HS, et al. Glucosamine and chondroitin for the treatment of osteoarthritis. World Journal of Orthopedics. 2017; doi:10.5312/wjo.v8.i1.1. There are some studies that show improved joint flexibility and range of motion with glucosamine sulfate,” says FarshadFaniMarvasti, MD, MPH, director of Public Health, Prevention, and Health Promotion at The University of Arizona. “That’s the one I would take if you’re going to take it for joint stiffness.”

It’s worth bearing in mind that studies on the benefits of glucosamine are limited. Some evidence suggests that taking these supplements for joint health may not have the effect you want. 9 It’s always a good idea to speak to your doctor if you are experiencing pain or other symptoms. Glucosamine and chondroitin are considered safe, with no serious side effects reported in studies. However, these supplements can interact with blood thinners like warfarin ( Coumadin). It is not certain whether chondroitin, glucosamine, and MSM is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. This product should not be used in place of medication prescribed for you by your doctor. Most studies have shown that both glucosamine and chondroitin are safe to use for most people and no serious side effects have been reported. Only mild side effects like stomach upset, nausea, and headache have been observed ( 13, 17).

They might also affect blood sugarlevels, and one small study found theyraiseeye pressure, which could increase the risk for glaucoma.If you have diabetes or glaucoma, you may need to avoid these supplements, or have your doctor monitor your blood sugar levels and eye pressure more closelywhile you take them. Similar results were observed in a 2018 analysis, where combined glucosamine and chondroitin didn’t significantly improve pain or stiffness. Meanwhile, chondroitin alone led to minor improvements in pain ( 13).

Glucosamine dosage

In a 2014 review of 43 studies on the use of chondroitin for osteoarthritis, chondroitin taken alone or with glucosamine showed significantly lower pain scores — with a 10% mean difference — compared with a placebo. However, the overall quality of studies was low ( 11). Those patients with multiple health conditions should be aware that current prescription medication may interact with dietary supplements, and they should consult their doctor so that side effects can be best monitored. Moreover, as with many supplements that have not been studied, the long-term benefits and safety of the chemical are unknown. These arthritis supplements are generally well-tolerated. However, side effects can occur. The most commonly reported side effects of glucosamine and chondroitin include: Though the two can be taken separately, glucosamine and chondroitin are commonly taken as a single supplement. This combination has been more extensively studied. These mixed recommendations may partially stem from the fact that the manufacturer and type of the supplements can result in different study results. For example, pharmaceutical-grade varieties appear more effective compared with over-the-counter options ( 4, 5). Summary

As a partner, you will help the Arthritis Foundation provide life-changing resources, science, advocacy and community connections for people with arthritis, the nations leading cause of disability. Join us today and help lead the way as a Champion of Yes. Trailblazer The usual dosage is 1000mg of glucosamine taken every day. You may need to adjust the amount based on your body weight too. 16 After 6 months, chondroitin sulfate led to similar pain scores as celecoxib and significantly lower scores than the placebo. Thus, the authors concluded that chondroitin sulfate may be an effective pain remedy for those with knee osteoarthritis pain ( 10). A 2022 analysis of eight studies that included nearly 4,000 people with knee osteoarthritis found no convincing evidence that glucosamine and chondroitin provided major benefit.The ideal form of glucosamine has also caused dissent in the research community. Some studies show an advantage to glucosamine sulfate; others to glucosamine hydrochloride.One study that compared the two glucosamine forms head to head found no real difference between them. MSM is a naturally occurring compound and its effects on inflammation have been extensively studied. There are many different brands of glucosamine and chondroitin, which are usually sold together as one arthritis supplement. Again, there is no government monitoring to ensure the purity of these products. Studies havealsodiffered on which of these supplements offers the greatest benefitfor OA. Some find chondroitinto be superior, others favor glucosamine, while still othersprefera combination of the two.“Evidence would favor the two,”D’Adamosays. “They’re typically bundled that way when you buy them.”