Broccoli Sprout Extract by LLS | Contains Activated Sulforaphane | 60 Capsules | 18,000mg of Whole Plant Equivalent per Serving | Sulforaphane Supplement | Potent Antioxidant Content

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May protect against sun damage. Studies suggest that sulforaphane may protect against ultraviolet (UV) skin damage caused by the sun ( 21, 22, 23). Animal, test-tube, and human studies have indicated that sulforaphane may offer a number of health benefits. May Have Anticancer Effects Nandini DB, Rao RS, Deepak BS, Reddy PB. Sulforaphane in broccoli: The green chemoprevention!! Role in cancer prevention and therapy. J Oral Maxillofac Pathol. 2020 May-Aug;24(2):405. doi: 10.4103/jomfp.JOMFP_126_19. Epub 2020 Sep 9. PMID: 33456268; PMCID: PMC7802872. Previous cell-based and human studies have indicated that sulforaphane exposure is associated with decreased breast cancer progression, including initiating cell cycle arrest and apoptosis ( Kuran et al., 2020). Sulforaphane treatment led to the inhibition of cell proliferation of breast cancer cells lines, MCF-7 and MDA-MB-231 and provoked cytotoxic activity by changing cysteine residues of the promyelocytic leukemia protein, known to promote proliferation of the MCF-7 breast cancer cell line ( Alhazmi et al., 2020). Sulforaphane has also been shown to modify cell migration and expression of epithelial mesenchymal transition markers that play a large role in breast cancer metastasis ( Bagheri et al., 2020). Due to the supportive mechanistic data, animal models and clinical trials have begun to evaluate the use of sulforaphane interventions for psychiatric outcomes, including depression, schizophrenia, and autism ( Panjwani et al., 2018). Acute and chronic consumption of sulforaphane consumption ameliorated anxiety and depressive-like behaviours in ICR and C57BL/6 mouse models (assessed using the novelty suppressed feeding test, open field and tail suspension tests) ( Wu et al., 2016; Yao et al., 2016). Notably, C57BL/6 male mice that received sulforaphane in conjunction with depression-inducing lipopolysaccharide, exhibited lower depressive behaviours on the tail-suspension test and forced swimming test compared to those that did not receive sulforaphane ( Zhang et al., 2017).

The Broccoli Sprout Extract has a distinctive broccoli smell as it is an extract but it is tasteless. Raw vegetables have the highest levels of sulforaphane. One study found that raw broccoli had ten times more sulforaphane than cooked broccoli ( 2). The study found that sulforaphane effectively reduced fasting blood sugar levels by 6.5% and improved hemoglobin A1c, a marker of long-term blood sugar control. These effects were particularly strong in participants who were obese with poor diabetes control ( 17). Overview: Love Life Supplements Broccoli Sprout Extract is a potent antioxidant complex containing the most researched and best known antioxidant sulphur compound, sulforaphane. Sulforaphane has been shown to be more potent than many other antioxidants, particularly after cell damage has already occurred. The effectiveness of sulforaphane in helping prevent common age-related diseases and support healthy cells is due to its ability to regulate important signalling pathways. Unlike taking isolated sulforaphane, by consuming broccoli sprout extracts you are getting a far greater concentration of this compound (up to 50 times greater) while also receiving the full spectrum of protective phytonutrients found alongside it in broccoli.Broccoli is a cruciferous vegetable in the same family as the cauliflower, cabbage and Brussels sprouts. Broccoli is high in fiber, great for helping digestion, and also contains a compound called sulforaphane, which stimulates enzyme production in the body. Enzymes are essential to life, accelerating chemical reactions in your cells to keep you alive.

Given the positive actions of glucosinolates are largely related to anti-inflammatory and antioxidant mechanisms, the consumption of cruciferous vegetables and their glucosinolates may also have beneficial outcomes on other health conditions. Although there are few studies investigating the impact of certain cruciferous vegetables on other chronic conditions, such as obesity, future studies are needed to further investigate the role of glucosinolates. Author Contributions Additionally, scientific studies have shown that water-soluble nutrients such as vitamin C and minerals are largely preserved when steamed, whereas they are dissolved in the cooking water when boiled. May treat certain symptoms of autism. A study in 29 young men with autism found that daily doses of 50–150 µmol of sulforaphane for 18 weeks improved symptoms of autism like social interaction and verbal communication ( 20). If you train hard or exercise very regularly, your body needs extra support to optimise recovery and prevent over-training symptoms like fatigue, mood swings, inability to relax, poor quality sleep, and decreased motivation. Sulforaphane from broccoli sprout extract increases exercise recovery and prevents over-training symptoms by activating cells’ antioxidant defences, protecting them from stress and ridding the body of excess free-radicals. By reducing oxidative stress, you’ll also be slowing your body’s ageing process too. [14] Broccoli Sprout Extract For Diabetes Sulforaphane has also been proposed to protect against osteoclastic bone destruction in vitro ( Luo et al., 2021). Sulforaphane can support osteoblast differentiation ( via epigenetic mechanisms) and expression of the osteoclast activator receptor activator of nuclear factor-κB ligand (RANKL) in osteocytes ( Thaler et al., 2016). Here, after sulforaphane was provided over 5week, the aforementioned effects correlated to a 20% greater bone volume in both normal and ovariectomized mouse models. Of note, no shifts in bone mineral density distribution were recorded. Ultimately, this led the authors to suggest that sulforaphane should be studied further due to its potential to counteract osteoporosis. Sulforaphane has also been studied for its potential benefits in osteoarthritis due to its reported antioxidant and anti-inflammatory properties. When a synthetic form of sulforaphane was orally supplemented to mice over 3months, osteoarthritis-related gait asymmetry was recorded in vehicle-treated STR/Ort mice but not in sulforaphane treated mice ( Javaheri et al., 2017). Sulforaphane treated mice also presented with improvements in trabecular and cortical bone, key indicators for bone strength. Noteworthy, favorable effects on bone turnover markers, such as C-terminal crosslinking telopeptide of type-I collagen (CTX-I; bone resorption marker) and total procollagen type 1 N-terminal propeptide (P1NP-bone formation marker), were recorded. CancerSulforaphane from broccoli sprouts is linked to preventing cancer, type 2 diabetes, and cardiovascular disease, as well as improving phase 2 detoxification and exercise recovery

Several human intervention trials have also been performed. In a 4-week parallel, randomized, double-blind placebo-controlled study including 81 human participants with type 2 diabetes, 10g/day broccoli sprout powder (225μmol sulforaphane daily) decreased fasting serum insulin and insulin resistance by 18.2 and 14.2%, respectively ( Bahadoran et al., 2012). Positive results were also seen in a randomized double-blind placebo-controlled study including 97 Scandinavian patients with type 2 diabetes. In this study, patients consumed broccoli sprout extract (150μmol sulforaphane/day) or a placebo over a 12-week period. The glucoraphanin-rich broccoli sprout extract improved both fasting glucose and HbA1c (7.38–7.04%) in obese patients with dysregulated diabetes (BMI >30kg/m 2; HbA1c > 50mmol/mol) ( Axelsson et al., 2017). The authors noted that this reduction in HbA1c was likely to reflect a clinically meaningful effect, as an HbA1c of 7% is the treatment goal of the American Diabetes Association ( Axelsson et al., 2017). In a recent 12-week randomized controlled parallel intervention trial, 92 patients with type 2 diabetes were randomized to one of three different diets: 500g/day bitter and strong-tasting root vegetables and cabbages, 500g/day mild and sweet-tasting root vegetables and cabbages, or 120g/day mild and sweet-tasting root vegetables and cabbages (normal diet) ( Thorup et al., 2021). Improvements in glycemic control were noted in both groups with increased vegetable intake; however, consumption of bitter and strong-tasting vegetables (including kale and cabbage) had the greatest improvements to fasting glucose (4-fold), total cholesterol (2-fold), and body fat mass (2-fold) ( Thorup et al., 2021). Hypertension Harvard Health. (2019). Phytonutrients: Paint your plate with the colors of the rainbow. [Online]. Harvard Edu. Last Updated: 2019. Available at: https://www.health.harvard.edu/blog/phytonutrients-paint-your-plate-with-the-colors-of-the-rainbow-2 [Accessed 6 December 2022].

Top 5 Benefits of Broccoli Sprout Extract & Sulforaphane

From seed to harvest, broccoli can take anywhere from 60 to 150 days to grow, depending on environmental temperature and broccoli type.

So if you want to get the most nutrients out of broccoli, you should eat it raw whenever possible, rather than cooking it. At higher temperatures, most of the nutrients are lost, leaving only a nutrient-poor plant. Bai Y, Wang X, Zhao S, Ma C, Cui J, Zheng Y. Sulforaphane protects against cardiovascular disease via Nrf2 activation. Oxid Med Cell Longev. 2015;2015:407580. doi:10.1155/2015/407580

Conflict of Interest

Yagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW. Broccoli or sulforaphane: Is it the source or dose that matters? Molecules. 2019;24(19):3593. doi:10.3390/molecules24193593 Broccoli and broccoli extract contain two vital nutrients for cognition and memory: vitamin K and choline. Vitamin K is in very few foods, but it’s key to maintaining healthy brain function, and may even prevent diseases like dementia and Alzheimer’s (x).