Liquipak BAC 50 - Benzalkonium Chloride Concentrated 5L

Product Information

Its biocidal efficacy depends on its capacity to act as a cationic surfactant in binding to and disrupting cellular and intracellular membranes, and associated biochemical processes. The study, which was undertaken and reported by a leading US developer, manufacturer and marketer of topical antimicrobial pharmaceuticals based on quaternary ammonium compounds, found that their own benzalkonium chloride-based sanitizer performed better than alcohol-based hand sanitizer after repeated use. Benzalkonium chloride also possesses surfactant properties, dissolving the lipid phase of the tear film and increasing drug penetration, making it a useful excipient, but at the risk of causing damage to the surface of the eye. CAS :91080-31-8; Chemical Name Quaternary ammonium compounds, benzyl-C16-22-alkyldimethyl,chlorides; Synonyms: benzyl-C16-22 -alkyldimethylammonium chlorides

The active is a cationic molecule offering good surfactant properties and can be formulated together with non-ionic and/or amphoteric surfactants. BACe is a quaternary ammonium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. The first step to the biodegradation of BAC is the fission or splitting of the alkyl chain from the quaternary nitrogen as shown in the diagram. Gossel, T A (1994). Principles Of Clinical Toxicology, Third Edition (3, illustrated, reviseded.). CRC Press. ISBN 9780781701259.

BAC50 is no longer permitted for the use as, or in preparations for the treatment of moss as moss has been reclassified as a plant and comes under the plant protection legislation. Bondurant, Sidney W.; Duley, Collette M.; Harbell, John W. (August 2019). "Demonstrating the persistent antibacterial efficacy of a hand sanitizer containing benzalkonium chloride on human skin at 1, 2, and 4 hours after application". American Journal of Infection Control. 47 (8): 928–932. doi: 10.1016/j.ajic.2019.01.004. ISSN 1527-3296. PMID 30777389.

Benzalkonium chloride is also used in many non-consumer processes and products, including as an active ingredient in surgical disinfection. Critical intermolecular interactions and tertiary structures in such highly specific biochemical systems can be readily disrupted by cationic surfactants. BAC is measured by grams of alcohol per deciliter of blood, or per 100 milliliters (mL) of blood. This means for every 100 mL of blood, there are 0.08 grams of alcohol. How many drinks is 0.08? BAC 50 is a human skin and severe eye irritant. It is a suspected respiratory toxicant, immunotoxicant, gastrointestinal toxicant, and neurotoxicant.BAC 50 is used in disinfectants and algaecides not intended for direct application to humans or animals Activity is more marked against Gram-positive than Gram-negative bacteria and minimal against bacterial endospores and acid-fast bacteria. detergent: A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. Newer formulations using benzalkonium blended with various quaternary ammonium derivatives can be used to extend the biocidal spectrum and enhance the efficacy of benzalkonium based disinfection products.