Myo-Inositol & D-Chiro Inositol | Hormone Balance for Women | Ideal 40:1 Ratio | Myo Inositol 2000mg, D Chiro 50mg | Vitamin B8 to Regulate Menstrual Cycle & Support Ovarian Health | SM Nutrition

Product Information

With a 2000mg extra-powerful formula which includes Myo-inositol and d-chiro inositol, the women’s supplement maintains the body’s ratio. This dietary supplement combines the popular nutrients Myo-Inositol and D-Chiro Inositol in a 40:1 ratio, which is the ratio in which these vitamin-like sugar compounds occur in the body naturally. A very recent study [ 45] evaluated the changes in the PK profile of MI absorption in humans when administered combined with DCI or with glucose transporter inhibitors, as compared to MI alone. At the end of this paragraph, we would like to briefly mention two studies with alpha-lactalbumin and MI. The daily treatment of mice with 420 mg/kg MI/DCI in a 40 : 1 molar ratio allowed investigators to obtain a rapid and almost full recovery from PCOS signs and symptoms.

Inositol is a biomolecule found naturally in humans that helps support normal and healthy blood sugar levels, hormone levels, ovarian and ovulatory function, and egg quality. PCOS patients tend to have a much higher level of DCI and very low levels of MI, leading to an abnormally low MI:DCI ratio of 0. Supplements can impact on a molecular level and some of our cells live for over 120 days before being replaced. Endogenous production of both inositol isomers varies depending on the needs of the specific target tissue [ 5]; as an example, in normal women, the plasma ratio of MI to DCI is 40 : 1 [ 6], while in ovarian follicular fluid the ratio is close to 100 : 1 [ 7]. The higher dose of DCI failed to reproduce the outcomes of the two previous studies [ 14, 15] in terms of improving ovulatory frequency.We’ve kept our myo-inositol at 2000mg per serving due to the decrease in testosterone levels and improvements to insulin sensitivity seen at this level. Combining treatment with myo-inositol andD-chiro-inositol (40:1) is effective in restoring ovary function and metabolic balance in PCOS patients. In 2007, a randomized controlled trial (RCT) was carried out with MI in 30 PCOS women undergoing ICSI; patients were administered 4 g MI daily starting from the day of Gonadotropin Releasing Hormone (GnRH) administration.

In consideration of this, it is quite surprising to see that available proposed treatments for PCOS also include high dosages of DCI and often seem to be chosen without consideration of the therapeutic rationale and target. If you breach these conditions and we take no action, we will still be entitled to use our rights and remedies in any other situation where you breach these conditions. Such therapeutic proposals do not take various features of inositol stereoisomers into consideration.I have not had a period for 9 months, 2 weeks of taking this and I had a full on cramping, miserable period and I couldn't be more thrilled about it! For other international countries, please contact us to find out if Theralogix products are available or can be shipped to your country.