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Two types of immune responses are separately regulated by cytokines that control two general subsets of helper cells known as Th1 and Th2. Knowing that Dendrobium drugs have been traditionally used in TCM preparations as a universal remedy, they are worth investigating by scientists who are looking for new natural ingredients, which could become a main feature in healthy aging.

Several studies were also focused on structure and bioactivities of polysaccharides from Dendrobium huoshanense. e. the amyloid plaques composed of amyloid β peptide (Aβ) and neurofibrillary tangles consisted of hyperphosphorylation tau protein [ 60]. This compound (3 µM) was found to be a potential anticancer agent for HRMPC by decreasing cellular glutathione, leading to a DNA damage response and cell cycle arrest at the S-phase.to produce synergism and enhance targeted health benefits (patents CN105441280, CN103566350, CN105748996, CN105494776). Both, AE and Dendronan ® were shown to be non-cytotoxic (even at a high concentration of 160 μg/mL) and can activate macrophages, resulting in enhancing phagocytic activity (Dendronan ® at 5-20 μg/mL and AE at 5-40 μg/mL in a dose-dependent manner). In the trachea and lungs, it can help expel sputum and lung residues within 2 hours, and dredge the airway. kDa) were mainly composed of mannose and glucose with a trace amount of galactose and arabinose [ 85].

Furthermore, this compound was found to induce apoptosis of colorectal cancer HCT-116 cells via tubulin depolymerization and DNA damage stress which leads to the activation of c-Jun NH2-terminal protein kinase and mitochondria-involved intrinsic apoptosis pathway [ 35]. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. In vitro, the extract induced cytotoxic response in a concentration-dependent manner, with an IC 50 value at 350 µg/mL, against Dalton’s lymphoma (DL) cells [ 24]. The hypoglycemic activities were based on the serum indices including blood glucose, glycosylated proteins and insulin levels, the changes in pathological morphology of the pancreas.The hypothesis that bibenzyls compounds may be neuroprotective against apoptosis induced by the neurotoxins has been tested. Taking dendrobium along with medications for high blood pressure might cause your blood pressure to go too low. Results demonstrated that erianin inhibits cell proliferation and induces cell cycle G2/M arrest in OS cells by regulating cell cycle-related proteins.

Four polyphenols from Dendrobium loddigesii, namely loddigesiinols G-J, together with crepiduatol B were evaluated for the α-glucosidase inhibitory activity using spectrophotometric method.Moscatilin (100 mg/kg) significantly suppresses breast cancer metastasis to the lungs and reduced the number of metastatic lung nodules and lung weight without causing any toxicity [ 57]. Suggesting that Dendrobium polysaccharides have the potential to be developed into natural hypoglycemic agents, four polysaccharides from Dendrobium huoshanense, D.

However, even though the DP administration ameliorated the expression of AQP-5 in SG, there was still a fair decrease in the DP group compared with the control group. It significantly inhibited growth of lung cancer cell line A549 and suppressed growth factor-induced neovascularization. The Chinese consider Dendrobium as one of the fifty fundamental herbs used to treat all kinds of ailments and use Dendrobium tonic for longevity.The highest value of IFN-γ was found in splenocyte culture medium treated with 200 mg/mL of HPS-1B23 in the presence of Concanavalin A (ConA) by the end of culture, which was 3.